The national heart lung and blood institute assembled an ad hoc working group to evaluate opportunities for new major clinical trials in the field of hypertension the mandate of this working group was to consider the possible designs of major randomized clinical trials focused on clinical outcomes that might merit significant investment by the . Large randomized clinical trials of treatments with blood pressure lowering drug regimens have a long history that is usually dated from the veterans administration since renamed the department of veterans affairs va cooperative study on antihypertensive drugs which reported results from 1967 1972. To the editor in their comprehensive review of trials examining the efficacy of antihypertensive medications since 1966 pfeffer and mcmurray nov 3 issue1 state since the risks and the . Clinical trials in hypertension 1 clinical trials in hypertension nidhi sharma 15crm2268 2 hypertension htn is a major public health concern affecting 26 of adults worldwide people with htn worldwide in 2000972 million increase in the number of adults with htn globally by 2025 60 percentage of all global healthcare spending attributable to treat high blood pressure 10 annual worldwide
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